Gamma-aminobutyric acid (GABA) is a major neurotransmitter widely distributed throughout the central nervous system. Because too much excitation can lead to irritability, restlessness, sleeplessness, and spasmodic movements, this excitation needs to be balanced with inhibition. GABA - the most important inhibitory neurotransmitter in the brain - can provide this inhibition, acting like a "brake" during times of runaway stress. In addition, studies also indicate GABA can promote relaxation and enhance sleep.

It is thought that either low GABA levels or decreased GABA function in the brain may have an adverse impact on neurological health.

The natural GABA in Thorne's PharmaGABA-PRO is produced via a fermentation process that utilizes Lactobacillus hilgardii, the bacteria used to ferment vegetables in the preparation of the traditional Korean cabbage dish known as kimchi. Clinical studies show this natural form of GABA can increase the production of alpha-waves in the brain, creating a profound sense of physical relaxation while maintaining mental focus. In contrast, the stress-related beta-waves in the brain are decreased. In addition to changes in brain waves, natural PharmaGABA has been shown to produce relaxation, as evidenced by reduced pupil diameter, heart rate, and two natural markers of stress salivary cortisol and chromogranin A. In a head-to-head, double-blind trial of natural PharmaGABA versus synthetic GABA, synthetic GABA did not demonstrate these positive effects.

Ingredients:

One Capsule Contains: Gamma-aminobutyric acid (GABA)** 100 mg.

**From PharmaGABA®, a more effective, non-synthetic, naturally fermented form of GABA. PharmaGABA® is a trademark of Pharma Foods International.

Other Ingredients: Hypromellose (derived from cellulose) capsule. May contain one or more of the following hypoallergenic ingredients to fill space - Cellulose, Silicon Dioxide, MagnesiumCitrateLaurate.

Suggested Use: One capsule three times daily, or as otherwise directed by a health-care practitioner.

Warnings

ALLERGY WARNING: This product is contraindicated in an individual with a history of hypersensitivity to any of its ingredients.

EXCIPIENT FREE: This product does not contain wheat, gluten, corn, yeast, soy, egg, dairy products, or artificial colors, sweeteners, or flavors. This product also does not contain lactose, palmitic acid, or magnesium, calcium, or vegetable stearates.

PREGNANCY WARNING: If pregnant, nursing, or trying to conceive, consult your health-care practitioner before using this product.

INTERACTIONS/CONTRAINDICATIONS: There are no known adverse interactions or contraindications at publication date.