Administration of folinic acid bypasses several steps required of folic acid to become this bioactive form of folate. Folinic acid is a more metabolically active form of folate, capable of boosting levels of the coenzyme forms of the vitamin in circumstances where folic acid has little to no effect. Another benefit of folinic acid is that it is the form of folate responsible for proper DNA and RNA synthesis. Thorne supplies 800 mcg of folinic acid in each capsule of Folacal.

It is important for women of childbearing age to get enough folic acid, not just those who are planning to become pregnant. Only 50 percent of pregnancies are planned, so any woman who could become pregnant should get enough folic acid every day, especially before conception and during early pregnancy.

Ingredients:

One Capsule Contains: Folate (as Calcium Folinate) 800 mcg.

Other Ingredients: Hypromellose (derived from cellulose) capsule. May contain one or more of the following hypoallergenic ingredients to fill space ? Magnesium Citrate, Leucine, Silicon Dioxide.

Suggested Use: One capsule daily, or as otherwise directed by a health-care practitioner.

ALLERGY WARNING: This product is contraindicated in an individual with a history of hypersensitivity to any of its ingredients.

EXCIPIENT FREE: This product does not contain wheat, gluten, corn, yeast, soy, egg, dairy products, or artificial colors, sweeteners, or flavors. This product also does not contain lactose, palmitic acid, or magnesium, calcium, or vegetable stearates.

PREGNANCY RECOMMENDATION This product is indicated for supplementation during pregnancy. As with any supplementation during pregnancy, it is recommended you discuss this with your health-care practitioner.

INTERACTIONS/CONTRAINDICATIONS: Folinic acid supplementation is not recommended concurrently with methotrexate cancer therapy, as it can interfere with methotrexate's anti-neoplastic activity; however, this folate source has not been shown to interfere with the anti-inflammatory activity of methotrexate. An individual taking methotrexate for psoriasis or rheumatoid arthritis can safely take a supplement containing folate.